Mast Cells and Chronic Prostatitis
Mast cells are a cause of chronic prostatitis. What are mast cells? Mast cells are part of the immune system. A mast cell is part of a group of cells called leukocytes, which are white blood cells. Plasma contains leukocytes and erythrocytes, which are red blood cells. Mast cells are kind of like an early warning system in the body. When they get stimulated by certain types of antibodies, they release chemicals that signal that there is an infection or injury in the body. Mast cells cause inflammation in an area, for example the prostate area. Inflammation can affect nerves, which leafs to chronic pelvic pain. That is why other seemingly unrelated conditions can cause inflammation that leads to prostatitis.
Two of the chemicals created by mast cells are heparin (allows blood to flow to the area and prevents clotting) and histamine (causes capillary walls to become more permeable and let substances through). Mast cells have an important role in allergic reactions because they make and release histamine. Histamine is released in response to a toxic substance or when the cells detect an injury. Sometimes the immune system malfunctions and releases an uncontrolled about of histamine. In some patients an autoimmune dysfunction or allergic reaction can be to blame as the root cause of chronic prostatitis/chronic pelvic pain syndrome.
Treatment for prostatisis caused by mast cells may include several simultaneous treatment programs. Besides medications and drugs for chronic protatitis, there are many natural prostatitis treatments. Natural therapies may include diet, food intolerance, food to avoid, and supplements that help with inflammation. There are several alternative prostatitis treatments for symptom relief that you can try such as sitz baths, heat therapy, biofeedback therapy, prostate massage, stress management techniques, cognitive behavioral therapy, and many others.
If your prostatitis is caused by mast cells, it is important to determine the trigger that is causing your mast cells to create inflammation, whether it is an allergen, illness, injury, or even stress, as psychological stress can alter the immune system. Understanding the cause may help you and your health care provider treat the source and help find the right prostatitis treatments for your source of inflammation.